Structural–functional coupling changes in temporal lobe epilepsy

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P8: Temporal Lobe Epilepsy and Mitochondrial Dysfunction

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About 30 years ago pioneering studies, particularly by English investigators, began to alert clinicians to the existence of the behavioural changes of temporal lobe epilepsy. Yet despite this long history, disputes continue about the status of this syndrome. A major cause, although not the exclusive one, of these disagreements is that the phrase 'behavioural change in temporal lobe epilepsy' ev...

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Comparison of temporal lobe epilepsy with hippocampal sclerosis and temporal lobe epilepsies due to other etiologies

  Background: This study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) with those who have temporal lobe epilepsy (TLE) due to other etiologies.   Methods : In this retrospective study all patients with a clinical diagnosis of TLE were recruited in a referral outpatient epilepsy clinic at Shiraz University of Medical Sc...

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The role of corticothalamic coupling in human temporal lobe epilepsy.

The EEG activity of the thalamus and temporal lobe structures (hippocampus, entorhinal cortex and neocortex) was obtained using intracerebral recordings (stereoelectroencephalography, SEEG) performed in patients with TLE seizures undergoing pre-surgical evaluation. Synchrony was studied using a statistical measure of SEEG signal interdependencies (non-linear correlation). The results demonstrat...

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ژورنال

عنوان ژورنال: Brain Research

سال: 2015

ISSN: 0006-8993

DOI: 10.1016/j.brainres.2015.04.052